Born in 1975 in a musical family. Studied at the specialised school of music of the St Petersburg Rimsky-Korsakov Conservatoire and subsequently in Paris at the Conservatoire national supérieur (class of Alain Marion) where he won first prize at the graduation exams. He completed his postgraduate studies at the Musikhochschule in Munich (class of András Adorján) in 2002. Since 1998 he has been a soloist with the Mariinsky Theatre Orchestra.

In 1993 Denis Lupachev was a prize-winner at the Virtuosi of 2000 festival, in 1997 he won the special jury prize at the international flautists’ competition in Kobe (Japan) and in 1999 he won the Leonardo de Lorenzo International Competition (Italy).

He has appeared as a soloist with the Vladikavkaz Symphony Orchestra, the St Petersburg Camerata and the Mariinsky Theatre Orchestra under such conductors as Tugan Sokhiev and Mikhail Agrest. Since 2010 he has frequently appeared with the State Academic Chamber Orchestra (Moscow) and the Novosibirsk Philharmonic Orchestra.

Regularly gives recitals both in Russia and in Europe, Japan and the USA including appearances at music festivals including the Saimaa Music Festival (Finland) in 2002, Musicare in Reggio Emilia (Italy) in 2001, the Leonardo De Lorenzo Festival in Viggiano (Italy) and Musical Olympus in St Petersburg (Russia) in 2000. In 2002 he performed at the Stars of the White Nights festival with the conductor Gianandrea Noseda in a programme featuring Denis’ father Vyacheslav Lupachev’s version for flute and oboe (Alexei Ogrintchouk) of Alfred Schnittke’s rarely performed Concerto Grosso No 1. In 2005 together with Boris Tishchenko he performed the latter’s Concerto for Flute, Piano and String Orchestra as part of the Russian Winter festival (Moscow).

Since 1998 Denis Lupachev has directed the Mariinsky Theatre Soloists ensemble which performs throughout the world, appearing in Paris at the Théâtre du Châtelet, in Eilat at the Red Sea Festival and the Mikkeli Music Festival. The ensemble has recorded two discs, Denis Lupachev appearing as director, producer and soloist.

From 2004 to 2007 eh taught at the St Petersburg State Conservatoire. He conducts master classes in Russia and in Italy. Since 2007 he has been involved in the project A River of Talents run by the St Petersburg House of Music, established with the support of young musicians.